Hot Topics  

ADAPTIVE CLINICAL DESIGNS/ADAPTIVE METHODS        

Adaptive Design in Clinical Research

Radical Change in Clinical Development

Selecting the Optimal Sample Size: Initial Realism or Adaptive Re-estimation

Are You Ready for Adaptive Clinical Development? Part 1 of 2

Are You Ready for Adaptive Clinical Development? Part 2 of 2

Recent Advances in Adaptive Clinical Trial Designs

Solving Complex Problems in Clinical Trial Supply Management

Novel Statistical Issues from the Regulatory Biostatistician’s Viewpoint

Future Advancements in Models and Algorithms for the Optimization of Clinical Trial Recruitment

Integrating Market Perspectives into R&D Strategy

APPROVAL PATHWAYS FOR PRODUCTS TO TREAT RARE DISEASES     

 

Biomarkers in Drug Development: What a Project Manager Needs

to Know and Do to Enhance Project Value

 

Global Oncology Product Development: Strategies for Successful

Selection of Patient Populations and Study Endpoints in Early

Phase Clinical Development

 

Arsenic and Old Lace II: Newer Aspects of QT Study Design,

Sample Size, FDA Feedback, and Oncology Considerations

 

Clinical Trial Data and Coding Processes

 

Harmonization of Requirements for the Preclinical Development of

Anticancer Drugs

 

Targeted Disease Approach Using Natural Health Products

 

Integrating Clinical Research with Clinical Care

 

BIOTECHNOLOGY     

 

Facilitating the Regulatory Approval of Products for Public Health

Emergencies: Emerging Infectious Diseases or Intentional Terrorist

Acts

 

Recent Advancement of Novel Biotechnology in the Asian Pacific Region

 

Hot Topics in Biotechnology

 

Gene Therapy Regulations for EU Clinical Trials

 

RNA Therapeutics: Bringing the Future of Biological and Medical

Innovation to Today

 

Current Experiences in Stem Cell Therapies

 

Biosimilars/Follow-on Biologics

 

Biotechnology-derived Products and the Immune System:

Management of the Effects of the Interaction(s)

 

Nanotechnology Task Force: Regulating Nanotechnology Products

 

Adding Value to Resource-constrained, Early-stage Biotechnology

Product Development from the Regulatory Perspective

 

Using Systems Biology to Advance Knowledge-based Drug

Development

 

Understanding the Regulation of Advanced Therapy Medicinal

Products in Europe

 

Biotechnology Venture Roundtable

 

An Honest Look at the eClinical Process: How Biotechnology Can

Learn from Best Practices Outside the Industry

 

Industry Insights: Forging Partnerships with NIH-sponsored Clinical

Trials and Networks

 

Becoming a Sponsor of Choice for Clinical Investigators

 

Issues and Case Studies in Safety Data Migration

 

How Much Information Technology Do Early Stage Biotechnology Firms Need?

 

Outsourcing Strategies and Trial Management in Asia

 

The State of Clinical Outsourcing: Results from a 2008 Industry

Survey with a Focus on Transforming Business Relationships

between Sponsors and CROs

 

Developing a Balanced Matrix and Maturing Product Development Teams

 

Identification of Opportunities between CRO and Pharma for

Synergistic Application of Lean Six Sigma

 

Enterprise Project Management in Pharmaceutical R&D: The Journey Continues

 

The Evolving Role of Project and Alliance Managers at Each Stage

of Product Development

 

Establishment of a Regulatory Function in a Startup

Biotechnology/Pharmaceutical Company

 

EU Variation Regulations Update

 

Review of ICH Q5AQ5E Guidances and Experiences

 

CBER Safety Initiatives's (Blood, Tissue, Vaccines)

 

Changing Procedures for Conducting Clinical Trials in Europe

 

New Strategies for Successful Licensing Acquisitions

 

Biotechnology R&D in Developing Countries: A Public-private

Partnership between the Ludwig Institute, a Brazilian

Entrepreneurship, and Health Institutes

 

CLINICAL AND REGULATORY CONSIDERATIONS FOR

PERSONALIZED MEDICINES

Drug Diagnostic Co-development: Implications for Biomarker

Validation and Personalized Medicine

Personalized Medicine and Its Impact on Drug Development and

Commercialization

Personalized Medicine: 2008 Update

Accelerating Research: Integrating Clinical Research with Clinical

Care

Emerging Clinical Documents for Medical Writers

 

COMBINATION DEVICE AND THERAPEUTIC PRODUCTS     

 

Modernization of FDA Postmarket Adverse Event Information Management

 

FDA Draft Guidance: Protecting the Rights, Safety, and Welfare of

Study Subjects

 

Issues and Case Studies in Safety Data Migration

 

Recent Advancement of Co-development of Medical Devices and

Drugs in the Asia-Pacific Region

 

Dealing with Potential Geno-toxic Impurities (GTIs) Especially in

FDC (Fixed Dose Combination) Drug Products for Global Clinical

Trials

 

RAHP Gold: Device Track Masters

 

CRITICAL PATH INITIATIVE        

 

The Impact of FDAAA and Health Information Technology

Interoperability Activities on Drug Safety, Implementation of

Standards, and Data Stewardship Principles

 

The Intersection of CDISC Standards with Research Site Processes

 

Facilitating the Regulatory Approval of Products for Public Health

Emergencies: Emerging Infectious Diseases or Intentional Terrorist

Acts

 

Recent Advancement of Novel Biotechnology in the Asian Pacific Region

 

Hot Topics in Biotechnology

 

Nanotechnology Task Force: Regulating Nanotechnology Products

 

Imaging Biomarker Data Management

 

Tools for Integration of Biomarkers

 

Drug-induced Liver Injury (DILI): How Well Do Preclinical and

Clinical Studies Predict Hepatotoxicity?

 

Improving the Quality and Implementation of Medical Imaging in

Clinical Trials: Industry/Academia/Government Consortia

 

Current Challenges and Future Solutions in the Development of

Therapeutic Options for Patients with Community acquired

Pneumonia (CAP): Clinical and Regulatory Perspectives

 

Standards Shock Therapy: Demystifying the Current and Future

Roles of CDISC and HL7 Standards for Clinical Research and

Regulatory Submissions

 

FDA and CDISC eSubmission Pilots

 

How Much Information Technology Do Early Stage Biotechnology Firms Need?

 

Consortium Efforts in Safety Biomarker Discovery and Qualification

 

Biomarkers in Drug Development: What a Project Manager Needs

to Know and Do to Enhance Project Value

 

Women’s Health under the FDA Critical Path Initiative

 

Facilitating Global Pediatric Drug Development: An Assessment of

Recent Experience

 

Critical Path Update for 2008

 

US-EU Agreement: Administrative Regulatory Simplification, the Next Phase?

 

Innovative Medicines and the EMEA

 

One-year Experience after FDA Guidance on the Target Product

Profile

 

Genomic (Surrogate) Biomarker in Therapeutic Trials

 

MULTINATIONAL CLINICAL TRIALS INCLUDING DEVELOPING COUNTIRES         

 

Effective Working with Investigative Sites: Essentials for Clinical

Trial Conduct in the Emerging World

 

Conducting Clinical Trials in China

 

Leveraging Technology to Build an IT Infrastructure for Global Clinical Trials

 

Emerging Clinical Documents for Medical Writers

 

Outsourcing Strategies and Trial Management in Asia

 

Outsourcing to India and China: Managing R&D Projects

 

The Next Generation of Project Managers: PMs as CEOs

 

Doing the Project Planning for Large Multinational Clinical Trials

 

Regulatory Strategies in Latin America: New Conquest for

Pharmaceutical Companies for Timely Submissions and Project

Startups in Mexico and Other Latin American Countries

 

Regulatory Requirements for Conducting Clinical Trials in India,

China, and Russia

 

Dealing with Potential Geno-toxic Impurities (GTIs) Especially in

FDC (Fixed Dose Combination) Drug Products for Global Clinical

Trials

 

Public-private Partnership on Clinical Research in the Asia-Pacific Region

 

Multiregional Clinical Trials: Evaluating the Pros and Cons

 

PATIENT RECRUITMENT AND RETENTION 

 

Accelerating Research: Integrating Clinical Research with Clinical Care

 

Proof-of-concept Clinical Trials and Achieving Enrollment Goals

through Centralized Recruitment Tools

 

Restructuring Protocol Design to Fit the Needs of the Research Subject

 

Global Patient Recruitment and Retention: Identifying and

Overcoming Barriers to Accelerate Patient Recruitment and

Retention Worldwide

 

The Third Annual Session on Investigator Budgets and

Reimbursement: The Impact on Patient Enrollment and Retention

 

The Six Risk Areas of Clinical Trial Patient Enrollment

 

Subject Recruitment in the US: Is It a Losing Proposition?

 

The Keys to Establishing Best Practices for Accelerated Study Startup

 

Patient Recruitment Strategies and Sites’ Perspectives

 

Data-driven Patient Recruitment: Tools for Early Planning and

Predictive Management

 

Global Oncology Product Development: Strategies for Successful

Selection of Patient Populations and Study Endpoints in Early

Phase Clinical Development

 

Site Relationship Management (SRM) Initiatives for Improving Site Performance

 

Going “Glocal”: The Trend in Global Patient Recruitment and Retention

 

Thirty Ways to Increase Enrollment at Your Site

 

Addressing the Adverse Impact of Increasing Protocol Complexity

on Study Conduct Performance

 

Patient Enrollment: Underrepresented Populations

 

Becoming a Sponsor of Choice for Clinical Investigators

 

Understanding Clinical Trial Volunteer Experiences and Physician

Referrals to Clinical Trials

 

Accelerated Recruitment Strategies for Global Megastudies

 

Electronic Data Capture as a Strategy to Enhance Complete Data

Capture, Site Satisfaction, and Participation in Registries and

Observational Studies

 

Meeting Clinical Research Challenges in India

 

Outsourcing to India and China: Managing R&D Projects

 

PEDIATRICS     

 

Facilitating Global Pediatric Drug Development: An Assessment of

Recent Experience

 

Emerging Clinical Documents for Medical Writers

 

Pediatric Drug Development

 

Incentives and Rewards for Innovation in Pharmaceutical Development

 

BPCA Reauthorized: What's Next?

 

Innovative Approval Paths Are Needed for Products that Treat Rare Diseases

 

Innovative Medicines and the EMEA

 

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