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5th DIA Cardiac Safety Workshop in Japan

Oct 23 2014 10:00AM - Oct 24 2014 4:30PM | KFC Hall 1-6-1 Yokoami Sumida-ku Tokyo 130-0015 Japan

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Overview 

CALL FOR ABSTRACTS
Submission Deadline: MAY 12, 2014
Author Notification: JUNE 30, 2014
To submit an abstract for the DIA Cardiac Safety Workshop, please go click on the DIA Get Involved link.

For inquiries about abstract submission,
please contact Keiko Cambridge, Event Planning Manager
tel: +81-3-5575-2130 Keiko.Cambridge@diajapan.org


The current cardiac safety paradigm based on S7B and E14 has largely eliminated new drugs with torsadogenic potential entering the market. However, since the paradigm cannot necessarily provide enough precise information to predict proarrhythmic effects of new compounds, pharmaceutical companies may have inappropriately discontinued the development of efficacious drugs solely due to their QT–interval prolonging property. At a FDA/CSRC/HESIsponsored Think Tank Meeting held at FDA Headquarters on July 23, 2013, a new cardiac safety paradigm was proposed. It involves the Comprehensive In Vitro Proarrhythmia Assay (multiple ionic current measurement, in silico proarrhythmia prediction model, and usage of human ventricular myocytes) and careful Phase 1 ECG assessment.

Can TQT studies be completely removed from the paradigm? What should an intensive ECG study be? How will the IQ-CRSC prospective study influence the new paradigm? Will the current S7B and E14 guidelines be revised or will new guidelines be drafted?

This is a challenging time. The 5th Cardiac Safety Workshop in Japan - Moving Towards Integrated Cardiovascular Risk Assessment Models - will deal with the above and other topics. The program committee is inviting authors to submit abstracts for review, for oral presentation at the main event.

Program Committee 

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Registration Fees 

Member

Charitable Nonprofit/Academia Member/Medicals
¥25000.00
Member Government
¥25000.00
Member Standard
¥59000.00
Member Standard (As of 10/03/2014)
¥64000.00

Non-Member

Charitable Nonprofit/Academia Nonmember/Medicals
¥40000.00
NonMember Government
¥25000.00
NonMember Standard
¥79000.00
Group Discounts

There are no group discounts for this event.

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